January 10 2008 (Vol.451 Issue.7175) English PDF 16.9MB
Cover: The fungus Phycomyces blakesleeanus a set of repetitive elements is found only on the chromosome containing the sex locus, suggesting a general mechanism for the early steps in the evolution of sex determination and sex chromosome structure in eukaryotes. On the cover, a spiralled hypha of a Phycomyces strain in which both sexM and sexP genes are co-expressed to induce the formation of this pseudo-sexual structure.
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